Ph.D., research associate professor,
Bolyai János fellow (2001-2004)
Mail address:
Department of Organic Chemistry, Eötvös L. University,
Budapest 112, Pf. 32. 1518
E-mail: bosze at elte.hu, szilvia.bosze at gmail.com
Tel: +36-1-372-2500 ext. 1409 or 1736
Fax: +36-1-372-2620
Degree
Year of PhD: 1999
University/Institution: Eötvös Loránd University
PhD registration number:P-139/1999
Languages
English: Advanced Level Write and read (C)
Russian: Basic Level Write and read (C)
Qualifications
1990: Biology and Chemistry, MSc, Eötvös Loránd University
Affiliations:
1991 - Research Group of Peptide Chemistry, Position: Research Associate Professor
1997 - Head of the Microanalytical Laboratory, Research Group of Peptide Chemistry
2012 - Head of the Cell culture and Immunochemical Laboratory, Research Group of Peptide Chemistry
Decorations:
1997 Certificate of Merit by National Scientific Student Council, Achievement: Supervision of student, 26th National Scientific Student Competition, 2nd prize
1998 Research Grant, by Soros Fundation, Achievement: grant for scientific work
1999 Certificate of Merit by National Scientific Student Council, Achievement: Supervision of students, National Scientific Student Competition, 3rd and 4th prize
1999 Publication Prize of Lajos Kisfaludy Foundation, by Lajos Kisfaludy Fundation, Gedeon Richter Plc.,Achievement: Reseach work, summarised in scientific paper "J. Peptide Research, 52, 216-228."
2000 Young Investigator Scientific Prize, by Hungarian Academy of Sciences, Achievement: Research work, PhD thesis
2001 János Bolyai Research Grant, by Hungarian Academy of Sciences, Achievement: research
2004 Certificate of Merit, by National Scientific Student Council, Achievement: Supervision of student, National Scientific Student Competition, 3rd prize
2005 Győző Bruckner Young Investigator Scientific Prize, by Győző Bruckner Foundation, Gedeon Richter Plc., Achievement: research
2010 Certificate of Merit by Sanofi-Aventis/Chinoin Research Prize, Achievement: Bioconjugate versus Mycobacterium tuberculosis, research summary
2011 Certificate of Merit by Hungarian Chemical Society, Achievement: Supervising MSC thesis (Zsuzsa Baranyai, I. Prize)
Role in scientific community:
1995 - Hungarian Biochemical Society
1999 - Public Body of Hungarian Academy of Sciences, member
1999 - member, Peptide Chemistry Comittee of Hungarian Academy of Sciences
2000 - European Peptide Society, member
2001 - Hungarian Society for Immunology, member
2001 - member, Hungarian Chemical Society
2010 - member, editorial board, Biochemistry
2011 - Secretary, Lajos Kisfaludy Foundation, Richter Gedeon Plc.
2015 - member, MTA Biologikum-analitikai Munkabizottság
2015 - board member, MKE Analitikai Szakosztály, Biologikum-analitikai Szakcsoport
Invited lectures (conferences, institutes):
2009 - Hungarian Biochemical Society, Annual Conference (2009), Section: Chemical Biology, "Biokonjugátumok versus Mycobacterium tuberculosis/Bioconjugates versus Mycobacterium tuberculosis
2010 - "Magyar Tudomány Ünnepe", A tuberkulózis terápia új megközelítési módszerei,
2012 - University of Zurich, Sciex-NMS, home mentor lecture, Organic Chemistry Institute, Application of Bioactive Peptides and Peptide Conjugates
2014 - Charles University, Why chemists are needed? In vitro evaluation of novel compounds
Faculty of Pharmacy, Hradec Králové, Csehország
2015 - 17th International Congress of the Hungarian Society for Microbiology, Budapest, "Combating Mycobacterium tuberculosis with novel compounds: host cell targeting strategies in a series of in vitro and in vivo models", invited semi-plenary lecturer
Organising international scientific conference:
2003 - Cellular Transport Strategies for Targeting, EU5 QoL Workshop, Budapest, Hungary
2014 - COST StemChem, CM1106, 2nd Working Group Meeting, Budapest, ELTE, organising comittee, co-Chair
Grants (as principal investigator):
FKFP, 0153/2001 (2001-2004) Modelling of exogen and endogen antigenes with synthetic peptides; optimizing epitope recognition and intracellular trafficing
Hungarian Scientific Research Fund (OTKA, F034886 (2001-2004) Synthesis of artificial antigens based on the structure modification of specific epitopes
Hungarian-Italian Intergovernmental Cooperation Program (TéT, NKTH, olasz-magyar, I-51/2003, OMFB-00623/2005 (2004-2008)) Development of synthetic antigens and analysis of their in vitro T-cell response
OM KMA, (2004) Infrastructure development of microanalytical laboratory
Hungarian-South-African Intergovernmental Cooperation Program (TéT, NKTH, dél-afrikai-magyar, ZA-22/2006, OMFB-00823/2007 (2008-2009)) Peptide based diagnostic reagents using synthetic peptide conjugates
Hungarian Scientific Research Fund (OTKA NKTH, K 68358 (2007-2011)) Immunodiagnosis and treatment of tuberculosis using synthetic peptides and peptide-conjugates (Handed over to NFÜ from 01/01/2012)
Hungarian-South-African Intergovernmental Cooperation Program (TéT, NKTH, dél-afrikai-magyar, ZA-11/2009 (2010-2011)) Boosting T cell based detection of Mycobacterium tuberculosis infection using synthetic antigens
Hungarian Scientific Research Fund (OTKA, K 104275 (2013-2017)) Detection of latent Mycobacterium tuberculosis infection and host cell specific targeted delivery of potential antituberculotic compounds
PhD supervision, co-supervisor (3 students as supervisor, 1 student ad co-supervisor) 2006- 2016)
Supervising Scientific Student Competition projects (TDK) (10 students from 1997-)
Theoretical course:
Chemical and functional characterisation of biologically active peptides in vitro
Practical courses:
Chemical and functional characterisation of biologically active peptides in vitro
Analytical laboratory practice, Elemental analysis
Maternity leave:
1997.02.01 - 1998.01.30
1999.11.01 - 2000.09.01
Scientometric data:
My publications according to the Collection of the Hungarian Scientific Work (MTMT): link
Number of publications in international peer-reviewed journals: 72
Number of publication in Q1 journals: 28
Sum of impact factors: 185.520
Number of independent citations: 458
Hirsch-index (according to the Web of Science): 15
Study trips (shorter than 3 months):
2004, (4 weeks) University of Palermo, Department of Biopathology and Biomedical Methodologies, Italy, Sponsor: Tudományos és Technológiai Alapítvány/Hungarian-Italian Intergovernmental Cooperation Program, Research topic: In vitro evaluation of Mycobacterium tuberculosis epitope peptides
2006, (3 weeks) University of Palermo, Department of Biopathology and Biomedical Methodologies, Italy, Sponsor: Tudományos és Technológiai Alapítvány//Hungarian-Italian Intergovernmental Cooperation Program, Research topic: In vitro evaluation of Mycobacterium tuberculosis epitope peptides
2008, (3 weeks) Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa, Sponsor: Tudományos és Technológiai Alapítvány/Hungarian-South-African Intergovernmental Cooperation Program, Research topic: Design and evaluation of data on epitope mapping of immundominant Mycobacterium tuberculosis proteins
2012, (1 week) University of Zurich, Sciex-NMS, home mentor, Organic Chemistry Institute, Sponsor: Sciex
