Szemelvények legújabb eredményeinkből:


Schuster, S; Juhász, É; Halmos, G; Neundorf, I; Gennari, C; Mező, G.:
Development and Biochemical Characterization of Self-Immolative Linker Containing GnRH-III-Drug Conjugates. INT. J. MOL. SCI. 23, 5071. (2022)
DOI: 10.3390/ijms23095071
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Horváth L. B.; Krátký, M; Pflégr, V; Méhes, E; Gyulai, G; Kohut, G; Babiczky, Á; Biri-Kovács, B; Baranyai, Zs; Vinšová, J; Bősze, Sz.:
Host cell targeting of novel antimycobacterial 4-aminosalicylic acid derivatives with tuftsin carrier peptides. EUR J PHARM BIOPHARM. 174: 111-130. (2022).
DOI: 10.1016/j.ejpb.2022.03.009
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Alaoui, N.-E.E; Boulhaoua, M; Hutai, D; Oláh-Szabó, R; Bősze, Sz;
Hudecz, F; Csámpai, A.:
Synthetic and DFT Modeling Studies on Suzuki–Miyaura Reactions of 4,5-Dibromo-2-methylpyridazin-3(2H)-one with Ferrocene Boronates, Accompanied by Hydrodebromination and a Novel Bridge-Forming Annulation In Vitro Cytotoxic Activity of the Ferrocenyl–Pyridazinone Products. CATALYSTS 12: 578. (2022)
DOI: 10.3390/catal12060578
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Szabó, I; Yousef, M; Soltész, D; Bató, C; Mező, G; Bánóczi, Z.:
Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System. Pharmaceutics 14, 907. (2022)
DOI: 10.3390/pharmaceutics14050907
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Baranyai, Zs; Biri-Kovács, B; Krátký, M; Szeder, B; Debreczeni, M L; Budai, J; Kovács, B; Horváth, L; Pári, E; Németh, Zs.; Cervenak, L.; Zsila, F.; Méhes, E.; Kiss, É.; Vinsova, J.; Bősze, Sz.:
Cellular Internalization and Inhibition Capacity of New Anti-Glioma Peptide Conjugates: Physicochemical Characterization and Evaluation on Various Monolayer- and 3D-Spheroid-Based in Vitro Platforms. JOURNAL OF MEDICINAL CHEMISTRY 64: 6 pp. 2982-3005., 24 p. (2021)
DOI: 10.1021/acs.jmedchem.0c01399
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Szabó, I.; Illien, F.; Dókus, E. L.; Yousef, M.; Baranyai, Zs.; Bősze, Sz.; Ise, S.; Kawano, K.; Sagan, S.; Futaki, S.; Hudecz , F.; Bánóczi, Z.:
Influence of the Dabcyl group on the cellular uptake of cationic peptides: short oligoarginines as efficient cell-penetrating peptides. AMINO ACIDS 53 pp. 1033-1049., 17 p. (2021)
DOI: 10.1007%2Fs00726-021-03003-w
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Mező, G.; Tripodi, A. A. P.; Ranđelovič, I.; Enyedi, K. N.; Biri-Kovács, B.; Tóvári, J.:
Asn-Gly-Arg szekvenciát tartalmazó ciklopeptidek alkalmazása a célzott tumorterápiában. MAGYAR ONKOLÓGIA 65: 2 pp. 113-120., 8 p. (2021)
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Kis, A.; Dénes, N.; Szabó, J. P.; Arató, V.; Beke, L.; Matolay, O.; Enyedi, K. N.; Méhes, G.; Mező, G.; Bai, P.; Kertész, I.; Trencsényi, Gy.:
In Vivo Molecular Imaging of the Efficacy of Aminopeptidase N (APN/CD13) Receptor Inhibitor Treatment on Experimental Tumors Using Ga-68-NODAGA-c(NGR) Peptide. BIOMED RESEARCH INTERNATIONAL 2021 Paper: 6642973 (2021)
DOI: 10.1155/2021/6642973
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Uzonyi, B.; Szabó, Zs.; Trojnár, E.; Hyvärinen, S.; Uray, K.; Nielsen, H. H.; Erdei, A.; Jokiranta, T. S.; Prohászka, Z.; Illes, Zs.; Józsi, M.:
Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder. FRONTIERS IN IMMUNOLOGY 12 Paper: 660382, 13 p. (2021)
DOI: 10.3389/fimmu.2021.660382
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Boulhaoua, M.; Pasinszki, T.; Torvisco, A.; Oláh-Szabó, R.; Bősze, Sz.; Csámpai, A.:
Synthesis, structure and in vitro antiproliferative effects of alkyne-linked 1,2,4-thiadiazole hybrids including erlotinib- and ferrocene-containing derivatives. RSC ADVANCES 11 : 46 pp. 28685-28697., 13 p. (2021)
DOI: 10.1039/D1RA05095H
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Biri-Kovács B, Adorján A, Szabó I, Szeder B, Bősze Sz, Mező G:
Structure-Activity Relationship of HER2 Receptor Targeting Peptide and Its Derivatives in Targeted Tumor Therapy.
Biomolecules 10(2), 183. (2020)
DOI: 10.3390/biom10020183
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Bősze Sz, Zsila F, Biri-Kovács B, Szeder B, Majer Zs, Hudecz F, Uray K:
Tailoring uptake efficacy of HSV-1 gD derived carrier peptides.
Biomolecules 10(5), 721 (2020)
DOI: 10.3390/biom10050721
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Dókus LE, Lajkó E, Ranđelović I, Mező D, Schlosser G, Kőhidai L, Tóvári J, Mező, G:
Phage Display-Based Homing Peptide-Daunomycin Conjugates for Selective Drug Targeting to PANC-1 Pancreatic Cancer.
Pharmaceutics 12(6), 576. (2020)
DOI: 10.3390/pharmaceutics12060576
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Fodor KJ, Hutai D, Jernei T, Takács A, Szász Z, Sulyok-Eiler M, Harmat V, Oláh-Szabó R, Schlosser G, Hudecz F, Kőhidai L, Csámpai A:
N-Alkyl-2-[4-(trifuoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity.
Molecules, 25(7), 1599. (2020)
DOI: 10.3390/molecules25071599
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Krátký M, Baranyai Zs, ©těpánková ©, Svrčková K, ©varcová, M, Stolaříková J, Horváth L, Bősze Sz, Vinąová J:
N-Alkyl-2-[4-(trifuoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity.
Molecules, 25(10), 2268 (2020)
DOI: 10.3390/molecules25102268
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Pethő L, Kasza Gy, Lajkó E, Láng O, Kőhidai L, Iván B, Mező G:
Amphiphilic drug-peptide-polymer conjugates based on poly(ethylene glycol) and hyperbranched polyglycerol for epidermal growth factor receptor targeting: the effect of conjugate aggregation on in vitro activity.
Soft Matter 16(24), 5759. (2020)
DOI: 10.1039/d0sm00428f
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Steckel A, Uray K, Schlosser G:
Detection of protein posttranslational modifications by mass spectrometry.
In: Amino Acids, Peptides and Proteins: Volume 44. (Editors: Maxim Ryadnov, Ferenc Hudecz) pp 140-170. (2020)
DOI: 10.1039/9781788017008-00140
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Tripodi, AAP. Ranđelović I.; Biri-Kovács B.; Szeder B.; Mező G.; Tóvári J:
In Vivo Tumor Growth Inhibition and Antiangiogenic Effect of Cyclic NGR Peptide-Daunorubicin Conjugates Developed for Targeted Drug Delivery.
Pathology and Oncology Research, 26(3), 1879. (2020)
DOI: 10.1007/s12253-019-00773-3
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Zsila, F.; Bősze, Sz.; Beke-Somfai, T:
Interaction of antitubercular drug candidates with ?1-acid glycoprotein produced in pulmonary granulomas.
International Journal of Biological Macromolecules, 147, 1318. (2020)
DOI: 10.1016/j.ijbiomac.2019.10.096
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Szabó I, Bősze Sz:
Az Aminosav analízis múltja és jelene a Peptidkémiai Kutatócsoport és az ELTE TTK Kémiai Intézet Szerves Kémiai Tanszék Mikroanalitikai Laboratóriumában.
BIOKÉMIA: XLIV : 4 , 12-26.(2020)
ISSN 0133-845
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