Szemelvények legújabb eredményeinkből:


Horváti, K., Bacsa, B., Mlinkó, T., Szabó, N., Hudecz, F., Zsila, F., Bősze, Sz.:
Comparative analysis of internalization, haemolytic, cytotoxic and antibacterial effect of membrane active cationic peptides: aspects of experimental setup.
Amino Acids 49 (6) 1053–1067(2017)
DOI: 10.1007/s00726-017-2402-9
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Orosz Á, Bősze S, Mező G, Szabó I, Herényi L, Csík G.:
Oligo- and polypeptide conjugates of cationic porphyrins: binding, cellular uptake, and cellular localization.
Amino Acids 49(7):1263-1276 (2017)
DOI: 10.1007/s00726-017-2428-z
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Podolski-Renic, A., Bősze, Sz., Dinic, J., Kocsis, L.,Hudecz, F., Csámpai A., Pesic, M.:
Ferrocene - cinchona hybrids with triazolyl-chalcone linker act as pro-oxidants and sensitize human cancer cell lines to paclitaxel.
Metallomics 9: 1132-1141 (2017)
DOI: 10.1039/C7MT00183E
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Sebestyén, M., Szabó, R., Kőhidai, L., Pállinger, É., Mező, G., Kóczán, Gy., Hudecz, F.:
Synthesis, conformation and cytotoxicity of new, branched polymeric polypeptides containing hydrophobic amino acid or arginine moiety.
Structural Chemistry, 28(2): 527-536 (2017)
DOI: 10.1007/s11224-016-0901-z
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Szabó, R., Sebestyén, M., Kóczán, Gy., Orosz, Á, Mező, G., Hudecz, F.:
Cellular uptake mechanism of cationic branched polypeptides with poly(L-Lys) backbone.
ACS Combinatorial Science, 19: 246-254 (2017)
DOI: 10.1021/acscombsci.6b00133
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Enyedi, K.N., Tóth, S., Szakács, G., Mező,G.:
NGR-peptide-drug conjugates with dual targeting properties.
PLoS One, 12(6): e0178632 (2017)
DOI: 10.1371/journal.pone.0178632
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Kapuvári B, Hegedüs R, Schulcz Á, Manea M, Tóvári J. Gacs A, Vincze B. Mező G:
Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice.
Invest. New Drugs 34: 416-423 (2016)
DOI: 10.1007/s10637-016-0354-7
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Bősze, Sz., Hudecz, F.:
Proteins and peptides for the immunodiagnosis and therapy of Mycobacterium tuberculosis infections.
Amino Acids, Peptides and Proteins (Eds. Ryadnov, M., Hudecz, F.), Royal Society of Chemistry, 146-198 (2016)
DOI:10.1039/9781782622680-00146
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Szabó, I., Orbán, E., Schlosser, G., Hudecz, F., Bánóczi, Z.:
Cell-penetrating conjugates of pentaglutamylated methotrexate as potential anticancer drugs against resistant tumor cells.
Eur. J. Med. Chem., 115, 361-368 (2016)
DOI: 10.1016/j.ejmech.2016.03.034.
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Knapp, K., Majer, Zs., Schlosser, G.:
The advantage of 7-diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin fluorogenic tagging of sulfhydryl groups in oligopeptides for tandem mass spectrometry.
Journal of Mass Spectrometry, 51: 476-478 (2016)
DOI: 10.1002/jms.3767
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Pozsgay, J., Babos, F., Uray, K., Magyar, A., Gyulai, G., Kiss, É., Nagy, Gy., Rojkovich, B., Hudecz, F., Sármay, G.:
In vitro eradication of citrullinated protein specific B-lymphocytes of rheumatoid arthritis patients by targeted bifunctional nanoparticles.
Arthritis Research & Therapy, 18: 15-27 (2016)
DOI: 10.1186/s13075-016-0918-0
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Szabó, I., Bősze, Sz., Orbán, E., Sipos, É., Halmos, G., Kovács, M., Mező, G.:
Comparative in vitro biological evaluation of daunorubicin containing GnRH-I and GnRH-II conjugates developed for tumor targeting.
J. Peptide Science 21: 426-435 (2015)
DOI: 10.1002/psc.2775
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Baranyai, Zs., Krátký, M., Vinšová, J., Szabó, N., Senoner Zs., Horváti, K., Dávid, S., Bősze, Sz.:
Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates.
Eur. J. Med. Chem. 101: 692-704 (2015)
DOI: 10.1016/j.ejmech.2015.07.001
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Uray, K., Hudecz, F.
Identification and structural modifications of synthetic antigens.
Amino Acids, Peptides and Proteins (Eds. E. Farkas, M. Ryadnov), Royal Society of Chemistry, London Vol. 39: 21-67 (2015)
DOI: 10.1039/9781849739962-00068
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Horváti, K., Bacsa, B., Kiss, E., Gyulai, G., Fodor, K., Balka, G., Rusvai, M., Szabó, E., Hudecz, F., Bősze, S.
Nanoparticle encapsulated lipopeptide conjugate of antitubercular drug isoniazid: in vitro intracellular activity and in vivo efficacy in a Guinea pig model of tuberculosis.
Bioconjug. Chem., 25: 2260-8 (2014)
DOI: 10.1021/bc500476x
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Schreier, VN., Pethő, L., Orbán, E., Marquardt, A., Alina Petre, BA., Mező, G. Manea, M.
Protein Expression Profile of HT-29 Human Colon Cancer Cells after Treatment with a Cytotoxic Daunorubicin-GnRH-III Derivative Bioconjugate.
PLOS One (2014)
DOI: 10.1371/journal.pone.0094041.g001
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